Research and Clinical Instruments Manufacturer & Supplier
AmplifiersNeuroLog SystemD360 8-Ch. EP/EEG/EMGD440 2/4 Ch. EMG/EPHEKA EPC10 Patch ClampHEKA EPC10 2/3/4 Ch. Patch ClampHEKA EPC800 Patch ClampAnti-vibration SystemsThorLabs Science DesksNarishige ITS Anti-vibrationNarishige Double MagnetNarishige SBP-2 BaseplateCell InjectorsPLI-100A Pico-injectorPLI-10 Pico-injectorNarishige IM-11-2Narishige IM-9BNarishige IM-9CNarishige IM-6Narishige IM-400Injection Accessories
Incubators & ChambersAutomate Perfusion ChambersMedical Systems MicroincubatorsSSD Brain Slice ChambersIontophoretic DevicesD380 Dye MarkerMains Noise EliminatorsHumBug Noise EliminatorD400 Mains Noise EliminatorMicromanipulatorsElectrophysiology System ManipulatorsInjection System ManipulatorsStereotaxic“YOU” CompactChronic ManipulatorsAccessoriesMicroscope Adaptors
MEA SystemsMED64 – BasicMED64 – Quad IIMED64 – AllegroMED64 – Plex 4/8MED64 – PrestoMED64 – Mobius SoftwareMED64 ProbesPerfusion SystemsStandard & Pressurized PerfusionSmartSquirt Micro-PerfusionIn Vivo Perfusion (Fixation)Heated PerfusionPipette FabricationMicropipette PullersMicroforges & MicrogrindersReplacement PartsCapillary GlassProgrammers & TimersDG2A Trigger Source
Signal GeneratorsTG315 Function GeneratorSoftwareQtracW Threshold TrackingAutoMate EasycodeHEKA Chartmaster SoftwareHEKA Patchmaster SoftwareHEKA Fitmaster SoftwareStimulatorsDS2A Constant VoltageDS3 Constant CurrentDS4 Biphasic Constant CurrentDS5 Bipolar Constant CurrentDS7A/DS7AH Constant CurrentDS7R Constant Current ResearchDS8R Biphasic ResearchD121-11 Mounting FrameD185 Transcranial MultiPulseD330 MultiStim SystemNL800A Current Stimulus Isolator
A/D Interface ModulesNL201 – Spike TriggerNL601 – Pulse IntegratorAmplifier ModulesNL100AK – HeadstageNL100RK (NL100AKS & NL100C)NL102G – DC PreamplifierNL104A – AC PreamplifierNL106 – AC/DC AmplifierNL108A – Pressure AmplifierNL109 – Bridge AmplifierNL120S – Audio AmplifierNL820A – IsolatorNL822 – Two Channel AC PreamplifierNL844 – Four Channel AC PreamplifierAnalogue ModulesNL254 – RatemeterNL506 – Analogue SwitchNL703 – EMG Integrator
Digital ModulesNL405 – Width/DelayNL501 – Logic GateNL505 – Flip FlopNL603 – CounterNL730 – Pulse ShiftFilter & Conditioner ModulesNL125/6 – Band-Pass FilterNL134/5/6 – Four Channel Low Pass FiltersNL143 – Three Channel Difference AmplifierNL144 – Four Channel High Pass FilterNL530 – Signal ConditionerNL540 – Inverting Attenuator (Alt. Gain)Generator ModulesNL301 – Pulse GeneratorNL304 – Period GeneratorNL412 – Pulse
Neurolog AccessoriesAccessory KitsAdaptors & Adaptor CablesSockets (for cable mounting)Sockets (for panel mounting)Plugs (for cable mounting)Extension CablesCablesElectrode HoldersMiscellaneous ItemsNeurolog System CasesNL900D NeuroLog System CaseNL905 Compact NeuroLog System Case
Pressure Transducers & AccelerometersPressure TransducersForce TransducersAccelerometersStimulator ModulesNL510 – Pulse BufferNL512 – Biphasic BufferNL800A Constant Current Stimulus Isolator
Amplifier Accessories D175 Electrode Impedance Meter D179 Performance Checker D360 Audio Interface D360 USB to Serial Adaptor D177 Bio-Feedback Unit Isolated Amplifiers for EMG / EEG D440 2 or 4 Channel Isolated Amplifier D360 8-Channel Patient Amplifier D360R 4 Channel Research Amplifier
Neurodiagnostic AccessoriesIntraoperative Monitoring (IOM) and Electroencephalography (EEG) Electromyography (EMG) Nerve Conduction Study (NCS) Evoked Potential (EP) Axelgaard Stimulation Electrodes
Peripheral Stimulators DS5 Isolated Bipolar Constant Current Stimulator DS7A & DS7AH HV Constant Current Stimulator NEW DS7R HV Constant Current Research Stimulator NEW DS8R Biphasic Constant Current Stimulator
Stimulator AccessoriesD188 Remote Electrode SelectorElectrode Connection HeadboxesTrigger CablesElectrode HoldersTranscranial Cortical StimulatorsD185 MultiPulse Cortical Electrical Stimulator
Cath SecureCATH-SECURE – OriginalCATH-SECURE – ExtendedCATH-SECURE PlusCATH-SECURE – Dual TabCATH-SECURE For KidsNG SECURE
PessariesPessary Ring Sizing KitsCerclage Pessary (Perforated)Cerclage Pessary (Non Perforated)Ring PessaryThick Ring PessaryCube Pessary (Perforated)Cube Pessary (Non-Perforated)Vaginal DilatorUrethra PessaryBowl PessarySieve Bowl PessaryHodge PessaryClub PessaryTandem Pessary (Perforated)Tandem Pessary (Non-Perforated)
Urodynamic ConsumablesUrodynamics CathetersPump Infusion SetsTransducer Pressure DomesUrodynamic Consumables Accessories
The HumBug Noise Eliminator is the ideal piece of biological research technology, aiding in reducing contamination in signal readings from biological sensors and high impedance devices.
A New Solution – 50 or 60Hz Noise Removal without Filtering
Publications which cite use of the Digitimer D185 can be found on Google Scholar.
The HumBug is NOT a mains noise filter, making this the main reason it is a special, perhaps unique product. Filtering often results in phase shifts, frequency loss, amplitude errors, DC shifts, time delays or digital distortion. The HumBug will eliminate 50/60Hz electrical interference (and harmonics) without altering your signal of interest.
A noisy waveform is the summation of two separate components. One component is the biological signal of interest and the other is noise of various forms. These forms of noise include random fluctuations generated by the sensor, amplifier and background biological noise in the vicinity of an experimental setup. The HumBug is designed to cancel electrical interference. It constructs a replica of noise embedded within the input signal and subtracts this replica from the noisy signal as it passes through the device. The end result is an output which contains only the signal of interest – mains noise removal without filtering.
The HumBug adapts rapidly when the input signal is dominated by noise and proceeds more slowly when low amplitude noise is embedded within continuous physiological activity. Adaptation is also slower for harmonics with frequencies greater than 1kHz.
Yes, but please remember that the HumBug is a single channel device, therefore you will need one HumBug for each channel of interest.
First you should check that the HumBug is configured to remove noise of the appropriate frequency. You can check this as it should be indicated next to the power connection socket on the back of the unit. It may be possible that the noise you are experiencing is not picked up from the mains supply. If the peak to peak noise is too large for the HumBug to completely cancel. If so, the indicator will continue to flash red. The HumBug cannot eliminate noise greater that 1V peak to peak. Likewise, low amplitude noise (<15mv) can be difficult to remove, so it is suggested that you increase the gain of your signal to ensure that the amplitude is greater than 15mV peak to peak.
It is possible, but not as easy as it seems to be at first glance. The problem is, that the EPC 10 has no Current In AD channel. The current signal from the amplifier board is hard wired with the AD converter inside the housing of the amplifier. Therefore it is not possible to connect the output of Filter 1 or Filter 2 via the HumBug and a Current In AD.
One would have to use one of the free AD inputs of the EPC 10 for reading the current signal. This has some drawbacks: the “real” current AD is automatically scaled by the “gain” that is set in the amplifier dialog. This is not the case for other AD inputs. As a consequence, you would have to scale the AD input manually (in the configuration dialog). This is no problem as long the gain is kept at the same value during an experiment. However, if the gain is changed frequently, then it might become annoying to change the AD scaling in the configuration many times.
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